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Worcestershire Health and Care NHS Trust
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National Institute for Health Research Portfolio Studies

The National Institute for Health Research has a database of clinical research studies taking place in the NHS that are funded by the life sciences industry and other funders including charities, central and overseas governments, investigator initiated commercial collaborative research, as well as the NIHR's own research programmes.

These are known as 'portfolio studies' and the Trust takes part in these because we know they are of the highest quality.

The studies currently open within the Trust are...

DNA Polymorphisms in Mental Illness for Schizophrenia 

This is a joint study between the University of Central London, the Mental Health Research Network and the Trust, gathering information attempting to identify the genes involved in the susceptibility of schizophrenia. The team at UCL are aiming to develop specialised interventions including reducing (or eliminating) side effects from medication.

 

Improving outcomes in adults with epilepsy and intellectual disability: A cluster randomised controlled trial of nurse-led epilepsy management (EpAID)

Nearly a million adults in England have an intellectual disability (ID). Epilepsy is the most common medical illness in this group, occurring in around 26%. In adults with ID and epilepsy there are suggestions that improvements may follow introduction of epilepsy nurse (EN) -led epilepsy care. This trial seeks to find out whether nurses with expertise in epilepsy and intellectual disabilities can improve clinical and quality of life outcomes in the management of epilepsy in adults with ID. 

EpAID logo

ATLAS A pragmatic randomised double-blind trial of Antipsychotic Treatment of very LAte-onset Schizophrenia-like psychosis

Very late-onset schizophrenia-like psychosis is a common condition, which affects an estimated 34,000 of the UK population aged over 60. After dementia and depression, these patients represent the largest diagnostic group presenting to Old Age Psychiatry services. The trial seeks to evaluate the effectiveness of prescribing the antipsychotic drug, amisulpride, and to gain a better understanding of the risk factors and natural history of late-onset schizophrenia-like psychosis and to identify patient characteristics predictive of response to anyipsychotic therapy.

 

MOCAM: Non-specific Mechanisms in Orthodox and Complementary Alternative Medicine (CAM) Management of Back Pain Additional Study of Consultations

The aim of the study is to examine the patient-practitioner relationship, and to investigate how different practitioners and patients talk with each other during treatments for back pain. We want to understand whether particular communication styles are linked to more successful treatments. In other words, do patients find treatments more or less effective depending on how their practitioner talks to them?

 

The use of guided self-help to support outpatient treatment as usual in Anorexia Nervosa

The study aims to investigate the feasibility and acceptability of using self-help materials, used with guidance, to the usual treatment for patients with Anorexia Nervosa.

Please click here for the Trust's R&D Operational Capacity Statement 

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