Welcome to our news section where you can keep up to date with all that is going on in research locally and nationally, along with professional training and qualification updates and study updates.

Local Research News

Local publications:

HWHCT Research Newsletters

December 2022:  Research December 2022 update.pdf [pdf] 1MB

October 2022:  Research October 2022 update.pdf [pdf] 451KB

August 2022:  August newsletter.docx [docx] 1MB

June 2022:  June 2022 .pdf [pdf] 725KB

April 2022:  April 2022 update.pdf [pdf] 738KB

February 2022:  February 2022 update.pdf [pdf] 324KB

December 2021: Research newsletter Christmas 2021.pdf [pdf] 4MB

CRN WM (Clinical Research Network West Midlands) Bulletin

Friday 16 December 2022

Friday 2 December 2022

Friday 18 November 2022

Friday 4 November 2022

Friday 21 October 2022

CRN WM (Clinical Research Network West Midlands) Wellbeing Bulletin

12.12.22: Support in the current climate

1.12.22: Wellbeing Bulletin - December 2022

14.11.22: Wellbeing Bulletin - November 2022

3.10.22: Wellbeing Bulletin - October 2022

Local research news:

UPDATE: Research Innovation and Improvement (I&I) projects: HaRV (HeAlth Research Vehicle) - Dec 2022

As part of the feasibility study looking at the practicalities and pro’s and con’s of HaRV, we would love to get some feedback from you – teams and staff within this Trust. We ask for 5 minutes of your time to complete this survey:

 As ever your feedback is invaluable so thank you in advance. We will share the results in due course.

Research collaborator launch - Nov 2022

We are really excited to launch a new role enabling people to get involved in research – the Research Collaborator. Similar to a ‘champion’ role, anyone and everyone who works within this Trust is welcome to get involved – you do NOT have to be clinically trained or have any research experience.

If you want to help us promote research within your teams as well as to patients, maybe learn something new, meet a group of like-minded people, and can give 1 hour a month (max), then we’d love to hear from you. We have already run 3 virtual Q&A sessions about the role which have been well attended but are very happy to organise more early in the new year. Please email: for further information.

A budding partnership: SW Healthcare outreach vaccination van and health research promotion - Oct/Nov 2022

It’s been a busy autumn with members of the R&D team joining the SW Healthcare vaccination van out and about in the Worcester area (only certain cohorts eligible – please check here).

From early 2021 up until summer 2022, SW Healthcare ran the 3 large Covid vaccinations centres in Worcestershire: The Artrix (Bromsgrove); St. Peter’s Baptist church, Worcester and at the Malvern showground. This autumn they’ve been at different community hubs making access to Covid boosters accessible and convenient for people.

Vaccinations are only available due to health research and EVERYONE involved in the process – study teams, Health Research Authority (HRA), National Institute for Health and Care Research (NIHR), clinicians within NHS Trusts etc and crucially people – like you and me – participating. So us promoting and chatting about research alongside the vaccination van seemed like a good match.

We have been warmly welcomed by the vaccination van teams and it has been great for us to properly pilot outreach research promotion. Engaging with the public in a familiar, local community place for them, not just clinical settings, has been fantastic both for the public and us, and something that we will continue to build on.

Research Innovation and Improvement projects - work starting September 2022

At the end of 2021 the 3 NHS Trusts across Herefordshire and Worcestershire, Worcestershire Acute Hospitals Trust, Wye Valley NHS Trust and us – HWHCT, were successful in a project funding bid from the Clinical Research Network West Midlands (CRN WM). It is GREAT that this funding has been secured allowing us time and resource to really focus on driving research forwards across the 2 counties. Things will really get started in September so keep an eye open for updates.

The 4 projects are:

HaRV: HeAlth Research Vehicle: A feasibility study will be completed on running a vehicle equipped to enable the research teams to promote and undertake health research off site at other medical sites i.e. GP practises, dentists etc, as well as non-medical sites such as libraries and supermarkets. The ethos of this project is very much ‘taking research to the people’ and making ourselves more visible and accessible.

A Research Van was launched in the Manchester area at the end of 2021. The below gives a flavour of what we would like to see here in Herefordshire and Worcestershire:

State-of-the-art Research Van available for research delivery across Greater Manchester (11.7.22)

A new state-of-the-art Research Van is available to support the delivery of research projects at community locations across the region. Read more here.

SHAREO: A full evaluation of how shared office resources can be more effective. A review of each element of the set-up process AND ongoing governance requirements of organisations across several organisations to identify opportunities for efficiency and improved quality of research, with a focus on digital opportunities for efficiency. A proposal for a new operating model along with making sites more attractive to commercial research.

MAPCOE: MAPP ing COllAbOrAting EMPOwEring sErviCEs: There is a vast untapped resource of potential engagement that we do not have capacity to identify, and in our current model, are unable to provide support to these services even if we did. We need to be able to map research interested clinicians across all professions and create a plan within each team of how they will engage with research without reliance on the research team. We need innovative ways to empower clinical services to deliver studies relevant to their clinical need. One way to do this will be to adapt the model of our research support so that we are able to increase the breadth of our services along with linking up to interested 3rd parties to ensure the population benefits from research.

- DIGENATE: Data and digital is a key theme of the CRN West Midlands Entry Plan and the NIHR. A Training Needs Analysis of digital skills in the Research Workforce across the West Midlands will be carried out. We will develop training packages that can be pre-recorded and be available online to the entire workforce across the West Midlands. We will identify further opportunities to digitalise operations to make research more efficient, shadowing the research workforce and developing solutions.

A remarkable year for research participation in the West Midlands - up by 52% (6.7.22)

Research in the West Midlands continues to thrive with the number of clinical trials that took place in the region  increasing by 52% in 2021/22 on the previous year. Read more here.

Award winning Research Team here at HWHCT! (7.6.22)

It was the ‘NIHR (National Institute for Health and Care Research) Clinical Research Network West Midland’s Awards’ last week which celebrates the huge range of clinical research taking place right here in the West Midlands - from COVID-19 vaccine studies to staff wellbeing on Paediatric Intensive Care Units.

This Trusts Research and Development Team is absolutely thrilled to announce that they were joint winners in the ‘Team of the Year’ award category! This award recognises the teams judged to have made the greatest contribution to clinical research in the region in the last 12 months. Members from the Research and Development Team were part of the Worcestershire Covid-19 Trial Response Team along with Worcestershire Acute Hospitals NHS Trust, CRN West Midlands Primary Care and Across Teams, University of Birmingham Students, which supported the delivery of the national priority Covid Trials. Read more here: Award winning Research Team attachment June 2022.docx [docx] 986KB

TrialBlazers: 16 – 29 May, and International Clinical Trials Day: 20 May

The National Institute for Health and Care Research (NIHR) national ‘TrialBlazers’ campaign took place from Monday 16 May to Sunday 29 May 2022, with a particular focus on International Clinical Trials Day on Friday 20 May. Find out more in our June 2022 newletter - the link is at the top of this page.

We're now on Instagram! (end of April)

Our Research and Development Instagram account opened on 29 April. It’s part of our wider plan to try and make health research more easily accessible and relatable to everyone alongside our Research twitter account:

There aren’t many NHS Trust Research and Development departments out there on Instagram so we’re trailblazers of sorts! If you’re on Twitter or Instagram please follow us and keep up to date with all things research.

Huge thanks to Mark Gallagher and Fern Berry for their support in getting us up and running.

CQC Preparation: Research-Ready Packs (end of April/May 2022)

Keen to spread the word about research but also to support staff ahead of a future CQC visit, the Research Team have posted out ‘Getting Research Ready’ packs to all Trust sites. These packs offer varying levels of information for both staff and patients including posters and leaflets to display in patient facing areas and quick guides for staff. The overview sheet in the pack gives a bit of background and explains what’s included. Please email us if you require further copies of anything that’s in the packs or if you have any questions.

Worcester University's Feel Good Fayre in celebration of University Mental Health Day: 15.3.22

We were really pleased to have been invited to the Feel Good Fayre at Worcester University on Tuesday 15 March 2022 and what a day it was! Our first F2F off site research promotional day this year and once again we were wowed by the the students' interest and openness whilst chatting about mental health research. We handed out over 80 goody bags with research information and a few goodies enclosed, and the GLAD study (genetic links to anxiety and depression) QR code was scanned countless times.

It was also great to catch up with colleagues from the sexual health and early intervention in Psychosis teams who were also there. 

Local participation in national research study published 21.12.21

Huge congratulations to Marti van der Linde (Community Paediatric Dietitian Worcestershire North) who, as part of a team, had their work published online in 'Nutrition in Clinical Practise' just before Christmas. This was a commercial study run by Nestle and looked to 'Monitor gastrointestinal tolerance in children who have switched to an “enteral formula with food-derived ingredients”: A national, multicenter retrospective chart review (RICIMIX study).'

To read the article and outcomes in full please click here

National Research news

The General Medical Council endorses promoting research for all doctors

We’re delighted to see the latest statement from the GMC promoting the importance of research and normalising research for all doctors. Their stated aim is to enable a culture in the workplace where doctors are encouraged to be research-aware and research-active. This announcement marks the culmination of 3 year’s work from the CRN NHS Engagement team, in discussions with GMC and other partners.


NIHR Scientists recognised in New Year Honours list (5.1.23)

The NIHR are delighted to recognise the wide range of current and former NIHR researchers and leaders who were recognised in this year’s New Year Honours list. Read more here.

First UK proton beam therapy trial for breast cancer launches (3.1.23)

A new trial is testing the benefits of proton beam therapy for certain patients with breast cancer for the first time in the UK. Read more here.

Molnupiravir does not reduce COVID-19 hospitalisations or deaths in vaccinated, high risk people (23.12.22)

Molnupiravir does not reduce hospitalisations or deaths among higher risk, vaccinated adults with COVID-19, NIHR-funded research has found. Read more here.

Revolutionary device set to transform prostate cancer diagnosis (21.12.22)

A revolutionary device funded by the NIHR can help to reduce the risk of infection during prostate cancer diagnosis, according to new research. The CamPROBE device will also help to save time and money. Read more here.

NIHR publishes its 2021-22 annual report (20.1.23)

The NIHR has published its annual report and accounts, highlighting milestones and achievements during 2021/22. Read more here.

£2.4million to fund largest-ever trial of ketamine-assisted therapy for alcohol disorder (19.12.22)

A new trial will investigate whether ketamine-assisted therapy could help alcoholics stay off alcohol for longer. Read more here.

NIHR appoints new Head of Sustainability (15.12.22)

Dr Sophia Lentzos has joined the NIHR as its first ever Head of Sustainability. Read more here.

World-first treatment for 'incurable' T-cell leukaemia (15.12.22)

A teenage girl's incurable cancer has been cleared from her body using genetically modified immune cells. It is the first time this form of the treatment has been used in a patient, thanks to research supported by the NIHR. Read more here.

NIHR announces funding for new Global Health Policy and Systems Research (14.12.22)

Eight new researcher-led projects have been awarded funding under the NIHR Global Health Policy and Systems Research (Global HPSR) programme’s most recent call to fund research to improve access to appropriate and affordable health services in low and middle income countries (LMICs), aligned with the aims of Universal Health Care and Sustainable Development Goal 3. Read more here.

£50m to accelerate Motor Neurone Disease (MND) research (13.12.22)

The NIHR will play a critical role in new government action speeding up research into Motor Neurone Disease (MND) across the UK, with immediate investment so patients can benefit from cutting edge treatment and medicines sooner. Read more here.

£1.95 million for new NIHR Collaboration to tackle multiple long term conditions (12.12.22)

The Department for Health and Social Care (DHSC), through the NIHR, is funding a new five-year Multiple Long Term Conditions (MLTC) Cross-NIHR Collaboration. Read more here.

Air pollution improved but more work needed, says CMO report (9.12.22)

Greater effort is needed to reduce air pollution, says the Chief Medical Officer Professor Chris Whitty in his new annual report. Read more here.

Significant gaps in child weight management services, NIHR study finds (6.12.22)

An NIHR funded study found 77% of NHS trusts in England don’t have a child weight management service.Read more here.

World first stem cell trial aims to revolutionise MS treatment (2.12.22)

A world-first trial will test if stem cell transplantation could be used as a first-line treatment for patients with 'highly active' and ‘aggressive’ forms of multiple sclerosis (MS). Read more here.

Home monitoring technology to help improve life for people living with respiratory conditions (30.11.22)

New research will investigate how machine-learning technology could help monitor patients with lung conditions in their own homes.Read more here.

New study will help rapidly find flu treatments this winter (29.11.22)

A new £2.9 million NIHR-funded and delivered trial aims to use pandemic lessons to find effective treatments for people hospitalised with severe flu. Read more here.

Study finds blood thinning drug does not improve recovery from severe COVID-19 (28.11.22)

A UK-wide trial has found that a drug used to reduce the risk of blood clots does not help patients recovering from moderate and severe COVID-19. Read more here.

NIHR pilot works to improve awareness and inclusion in research (25.11.22)

A pilot scheme designed to engage under-served communities and improve inclusion and representation in health and care research has been so successful that it is now being rolled out across England. Read more here.

NIHR reaffirms EDI commitment with range of new data and targets (25.11.22)

The NIHR has today published a range of new equality, diversity and inclusion (EDI) data. It provides the most detailed picture of the UK’s health research sector produced to date. Read more here.

Investigating effects of water fluoridation on children’s dental health (18.11.22)

Adding fluoride to water supplies may deliver a modest benefit to children’s dental health, finds an NIHR-funded study. Read more here.

Professional News, Training and Qualification updates


CRN (Clinical Research Network) Connect newsletters

Monday 30 January 2022

Monday 23 January 2022

Monday 16 January 2022

Monday 9 January 2022

Monday 19 December 2022

Monday 12 December 2022

NHS Research and Development Forum newsletters

January 2023

December 2022

November 2022

October 2022

August 2022

Be Part of Research Newsletter

Autumn (October) 2022

Summer (August) 2022

May 2022

Clinical Research Practitioner (CRP) Directory Bulletin (Homepage - Clinical Research Practitioners Directory - NIHR (

November 2022

October 2022

August 2022

Health Research Authority (HRA) Updates

January 2023

December 2022

November 2022

UK Community Nursing Research Forum (hosted by the Queen's Nursing Institute)

January 2023 newsletter

December 2022 newsletter

21.11.22 - Community Nursing Bitesize Research Masterclasses Also see below in 'TRAINING' section

November 2022 newsletter

September Newsletter - QNI Community Nursing Research Forum (

Community Nursing Research Forum (Community of Practice) (



Research Learning Lectures: CTIMP (Clinical Trial of an Investigational Medicinal Product) Study Regulations - 7.2.23, 2:00-3:00pm

This series of lectures for anyone in Health and Social Care interested in learning more about research covers a variety of topics relating to basic science, clinical trial methodology and statistics.

The lectures provide career advice for anyone who wishes to know more about research or work towards a career in research or academia. They are for:

  • Current Associate PIs
  • Associate PI Alumni
  • Health and Care professionals with an interest in learning more about research.
  • Those with an interest in learning about research delivery or research leadership
  • Those with an interest in a career in Clinical Academia

Future lecture dates:

ARDS subphenotypes - 28th March 2023, 4pm-5pm

Considerations from early career to successful female clinical academic - 4.4.23, 2pm-3pm

For further information and to book a place please click here.

ADVANCE DATE FOR THE DIARY: Research, the NHS and You - NIHR Conference for people new to research - September 2023 Full date and venue details to be confirmed in due course

  • Are you working within or with the NHS and curious about research with motivation to learn more?
  • Are you a healthcare professional who wants to explore how to combine reserach and service delivery in your busy working life?
  • Are you interested to find out the opportunities research could provide for your career development?

This one-day F2F event by the NIHR is designed for clinicians new to research. Click here to register.

The Queen's Nursing Institute (QNI): Mentorship Scheme - January 2023

Are you interested in becoming a research mentor or being mentored through your research and career development journey?

The QNI are excited to announce the launch of the Community Nursing Research Forum Mentorship Scheme to allow for more peer-support within community nursing research, as well as to forge links across networks. Click here to find out more.

The Research for Patient Benefit (RfPB) under represented disciplines and specialisms highlight notice: nurses and midwives

The Research for Patient Benefit (RfPB) programme invites applications from nurses and midwives to the first highlight notice of a series addressing NIHR strategy to strengthen careers of under-represented disciplines and specialisms.

The call offers researchers considerable flexibility to focus on any subject area or topic provided the application is within RfPB remit. All applications to this highlight notice must have a nurse or a midwife in an early stage of their research career as either the lead or joint-lead applicant. Read more here or contact us.

New course being run by the University of Birmingham 27/28 February 2023:

Improving clinical trial delivery: Investigator Site Staff. Please see the attachment below for further information.

Flyer_Improving Research Delivery_Investigator Site Staff (1).pdf [pdf] 240KB

The Queen's Nursing Institute (QNI) - Community Nursing Research Forum: Bitesize Research Masterclass - next one: 28.2.23: 1pm - 2pm

Click here for further info about joining this FREE series of bitesize events running on zoom. Save the below dates for future sessions into the new year:
- Writing for publication: tips from an editor w/ Prof. Catherine Walshe
Tuesday 28th February 2023 1pm - 2pm
- Introduction to qualitative data analysis: reflexive thematic analysis w/ Dr. Emma Roland
Thursday 16th March 2023 1pm - 2pm

Research and Development Forum 2023 (RDF23) conference: 21-23 May 2023

Bookings now OPEN for The NHS R&D Forum  RDF23 which will be taking place, in-person, at Sage in Newcastle/Gateshead on 21st-23rd May 2023. The event will be held in association with the Health Research Authority. The last in-person NHS R&D Forum Annual Conference was held in 2019. Click here for more information and here to book.

Associate Principle Investigator Scheme

The Associate PI Scheme is a six month in-work training opportunity, providing practical experience for healthcare professionals starting their research career.

People who would not normally have the opportunity to take part in clinical research in their day to day role have the chance to experience what it means to work on and deliver a NIHR portfolio trial under the mentorship of an enthusiastic Local PI. Click here for further information.

Improving Healthcare through Clinical Research - free online course: available from October 2022

During this course you will learn how medical treatments are discovered, tested and evaluated to improve healthcare for all. New research and delivery staff and those interested in a career in health research will find this course particularly valuable. The course runs for four weeks and you can join at any time. More information about MOOCs and other NIHR CRNCC online courses are available on the Future Learn website

Midlands Mental Health (MMH) and Neurosciences PHD Programme for Healthcare Professionals

The Midlands hosts the most innovative centres in mental health and neurosciences (MH&N), including digital mental health, clinical trials, neuroimaging, and epidemiology, serving an area of huge clinical need.

The Midlands Mental Health & Neurosciences PhD Programme is led by the University of Nottingham, in collaboration with University of Birmingham, University of Leicester, and University of Warwick, and our local NHS Trusts in the Midlands. Click here to find out more.

The NIHR-AoMRC Clinician Researcher Credentials Framework

A framework of master’s level qualifications is being developed jointly by the NIHR and the AoMRC, led by the Royal College of Physicians (RCP) to provide the necessary networks, skills and confidence needed for healthcare practitioners from any regulated profession to lead and support clinical research delivery.

It consists of two key elements:

Online modules - Flexible access to modules of high-quality interactive learning. These theoretical modules will develop knowledge and insight of the approaches to, and delivery of, clinical research.

Research Practice Experiences (RPE) – Practical modules that enable learners to take part in clinical research in their area of interest, as part of existing research studies, whilst being supported under the supervision and mentorship of a senior researcher. This will develop their experience and expertise to grow future local research leadership capability within the NHS. For more information visit here.


Alzheimer’s Society

Clinical training partnerships

The Alzheimer’s Society Clinical Training Partnerships are available for institutions with the capacity and infrastructure to support multiple clinical PhD candidates.

Clinical academics with institutional support can apply for up to three fellowships for clinicians or healthcare professionals to undertake a PhD. 

This scheme aims to work in partnership with institutions that wish to increase the numbers of clinicians and healthcare professionals working in the field of dementia. We wish to work with institutions that have high-quality research ideas, to attract outstanding clinicians or practitioners to undertake dementia research. 

Alzheimer’s Society funding is intended to cover up to 50% of the total cost of each fellow and a maximum of £150,000 can be requested for each post. The remaining funding should be available from other sources. 

Outline submission deadline: 24 Mar 2023

For more details please see:

Clinician and Healthcare Professionals Training Fellowship

Alzheimer’s Society’s Clinician and Healthcare Professionals Training Fellowship is ideal for all professionals working in clinical and health services who are looking pursue a PhD.

Applicants may apply for research costs to support their project. 

The award is open to all professionals working in clinical and health services looking to begin a career in dementia research. 

Clinicians, nurses and allied health professionals should have completed their professional training and hold registered membership of an appropriate body. 

Outline submission deadline: 24 Mar 2023

For more details please see:

Postdoctoral Fellowships

Alzheimer’s Society Postdoctoral Fellowships are ideal for anyone early in their research career. 

This fellowship allows exceptional early career researchers and final-year PhD students to apply for research funding to pursue a novel research idea and build their independent research portfolio. This fellowship is flexible and can cover a range of career stages.

Outline submission deadline: 24 Mar 2023

For more details please see:

Dementia Research Leader Fellowship

The Alzheimer’s Society Dementia Research Leader Fellowship is for exceptional researchers who want to build on several successful years of research and are ready to begin an independent research career.

Outline submission deadline: 24 Mar 2023

For more details please see:

Daphne Jackson Trust Fellowships

Alzheimer’s Society are proud to be partnering with Daphne Jackson Trust to sponsor a three-year fellowship for dementia researchers wanting to return to research. 

Grant deadline 30 January 2023

For more details please see:

Study updates

Psychological Impact of COVID-19 - intial results from phase 1 of the study (December 2021)

The Psychological Impact of COVID-19 (phase 1) looked at the psychological impact of the first lockdown, the relaxation of lockdown rules and the compulsory face coverings period. These inital results show the varying impacts of each of the above listed periods on different population sub groups - including gender, age, ethnicity and professional groups. Please click here to read the full article.

HUGE thanks to everyone who took part.

COPE-WM: Initial findings from this study were released 19.11.21

COPE-WM was a far reaching questionnaire study available to anyone who worked in healthcare. It closed at the end of September 2021.

The study released their initial findings on 19.11.21 which included:

  • Unsurprisingly those healthcare employees who had a positive COVID-19 test result were more likely to provide direct care to patients with COVID-19
  • There was poor infection control at the beginning of the pandemic but effective infection control measures were implemented after this initial period
  • Experience of working during the pandemic:
    • Demand as outstripping capacity
    • Peer support at work was as important as ever
    • Morally challenging decisions in the workplace
    • Mixed re-deployment experiences
  • Impact on mental health:
    • Mental health deterioration experienced during the pandemic
    • Uncertainty during the pandemic
    • Mental health coping mechanisms disabled
    • Working from home as problematic for mental health
    • Positive antibody rates:
    • Prior to vaccination 46% of participants had had a COVID infection (included study participants who had answered ‘yes’ as being symptomatic who then qualified to receive an antibody test kit)
    • From December 2020 rates of antibody positivity rise dramatically following the 1st and 2nd dose of vaccination to 98+%
  • A study coming in the new year – COCO – will further look into the issues raised here

They have only released preliminary findings including the above so we will share the full report once it’s released.

We’ve also received a request from the study regarding the follow up survey:

‘Thank you to everyone that took the time to complete the COPE-WM study baseline survey. If you completed the baseline survey and this was more than 4 months ago you should have received an email asking you to complete the follow up survey for the study. The email was sent to the email address you provided when asked for your personal email address when you completed the baseline survey. Thank you to everyone who has already completed their follow up survey.

Please be aware that for some participants the COPE-WM study emails have been filtered to their spam/junk folder – please check there if you think you should have received an email

If, however, you received a request email but have not yet completed the survey we would encourage you to do so to ensure your follow up data contributes to the study outcomes. Survey completion should take no more than 20 minutes of your time.

If you took part in the study more than 4 months ago and either have not received an email request to complete the follow up survey or remember receiving one but are no longer able to access it and would like to complete the survey please contact the study research team by email: .

If you took part less than 4 months ago please keep an eye out for the email about the follow up that you should receive in the next few weeks. 

The higher the number of participants who complete their follow up survey the better the study will be able to understand the impact of COVID-19 on people working in healthcare settings.’

THANK YOU once again to everyone who took part in this study.

iMCSP (individualised Meeting Centres Support Programme) – initial findings

We were involved in this research study a few years ago so please click below for the results: CIA_A_212852 1527..1553 ( Thank you to those who were involved.

SYMBAD trial results - October 2021

HWHCT took part in this trial so we were really pleased to receive these results at the end of October 2021. The main results have been published in the Lancet: but please see below for the summary outcomes:

‘In summary we found that there was no benefit in taking mirtazapine compared with placebo, there was even the possibility of harm with a marginally higher rate of mortality in the mirtazapine group. The clear conclusion from the data is that they do not support the use of mirtazapine as a treatment for agitation in dementia. Positively there was clear recovery in those that participated in both the placebo and the mirtazapine group. This means that the best thing to do clinically may be to actively monitor agitation while carrying out treatment as usual, rather than jumping to use another medication in all but the most serious of cases.

This is a result that has important implications to clinical practice, and we hope that you will join with us in disseminating the findings as widely as possible. There has been a press release: Research news - Common antidepressant should no longer be used to treat people with dementia - University of Exeter by the University of Plymouth and the team would be happy to work with your local institutions and Trusts should you wish to provide further public information. Alzheimer’s Research UK has also published an article: Antidepressant drug doesn’t improve agitation in dementia trial - Alzheimer's Research UK (

HUGE thanks to everyone who was involved in this study at HWHCT.

PrEP Impact Trial – A pragmatic health technology assessment and implementation.

PrEP (HIV Pre-exposure Prophylaxis) is a medicine for HIV negative people and it can reduce the risk of catching HIV when taken as instructed. However this is currently not available through the NHS.

PrEP is made up of two drugs, Tenofovir and Emtricitabine. Both these drugs have been widely used for many years to treat HIV and the drug has been used by several thousands of HIV negative people worldwide to reduce the risk of HIV.

To plan a PrEP programme in England, NHS England and Local Authorities carried out research to find out:

  • How many people attending sexual health clinics need PrEP?
  • How many of these start PrEP?
  • How long do they need PrEP for?

In this Trust the study ran across the 3 Sexual Health Services; Arrowside, John Anthony Centre and Hereford and 64 patients were recruited. All participants in this study had access to PrEP.

This study has now closed but we will share the outcomes when they are published later this year. A huge thank you to everyone who was involved.